AAP 2022 Bilirubin Tool
This is the AAP 2022 neonatal hyperbilirubinaemia calculator for infants born at 35 or more weeks' gestation, implementing the American Academy of Pediatrics' 2022 Clinical Practice Guideline Revision (Kemper AR, Newman TB, Slaughter JL, et al. Pediatrics. 2022;150(3):e2022058859). Given gestational age, postnatal age, and a total serum bilirubin (TSB) value, it looks up hour-specific phototherapy and exchange-transfusion thresholds and classifies the result as below-threshold, phototherapy, escalation of care, or exchange transfusion. It also accounts for neurotoxicity risk factors, which shift the infant onto a lower threshold curve, and can calculate a bilirubin:albumin ratio when albumin is entered. In the app, this ≥35-week AAP 2022 pathway sits alongside a separate NICE CG98-based tool for infants born below 35 weeks.
It's built for infants born at 35 or more weeks' gestation; the app provides a separate NICE CG98-based calculator for infants born below 35 weeks.
The app explicitly states to use TSB, not TcB, for all treatment decisions.
It flags a TSB within 2 mg/dL of the exchange-transfusion threshold. The app's guidance is to escalate to intensive phototherapy plus IV hydration, obtain STAT labs, and consult a neonatologist about NICU transfer.
No — the app's own guidance states you should NOT subtract direct bilirubin from TSB when using these thresholds.
Presence of neurotoxicity risk factors shifts the infant onto a lower, more conservative threshold curve, since the AAP 2022 guideline recommends treating at lower TSB levels when these risk factors are present.