Disease activity in the preceding 10 days. Weighted descriptors.
The SLEDAI-2K — SLE Disease Activity Index is a rheumatology scoring tool used in paediatric practice. Disease activity in the preceding 10 days. Weighted descriptors. It scores 24 criteria and interprets the total across 5 bands, so the number always arrives with the severity it implies rather than on its own. In PediAid each criterion is shown as a labelled option with the weight it carries, so the total can be checked rather than taken on trust.
24. They are Seizure (recent onset, excluding metabolic/infectious/drug causes); Psychosis; Organic brain syndrome; Visual disturbance (retinal changes of SLE); Cranial nerve disorder; Lupus headache (severe, persistent, narcotic-resistant); and others.
The total is interpreted as: any score - No activity: sLEDAI 0 - no disease activity in the last 10 days; 1 point or more - Mild activity: sLEDAI 1-5 - mild activity. Usually managed with hydroxychloroquine ± low-dose steroid; 6 points or more - Moderate activity: sLEDAI 6-10 - moderate activity. Escalate immunosuppression; a change of ≥4 points indicates a clinically meaningful flare; 11 points or more - High activity: sLEDAI 11-19 - high activity. Intensive immunosuppression required; 20 points or more - Very high activity: sLEDAI ≥20 - very high activity, often with major organ involvement. Urgent intensive therapy and specialist input.
No. It is a structured way to record and communicate severity. A clinician concerned about a child should act on that concern regardless of the total.
Total possible 105. SLEDAI-2K differs from the original by allowing persistent (not only new) rash, alopecia, mucosal ulcers and proteinuria to score.
Yes. Score definitions are bundled with the PediAid app, so the score computes without a connection.